Llegaste aquí para descargar Neural Control of Renal Function, Second Edition en pdf y otros formatos. Bajar Neural Control of Renal Function, Second Edition epub es sencillo. Aquí tienes toda la información necesaria.
¿De qué se trata este título?
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.
Acerca de Ulla C. Kopp
Ulla C. Kopp is Professor Emerita of Internal Medicine/Nephrology and Pharmacology at the University of Iowa Carver College of Medicine, Iowa City, Iowa. She received her Ph.D. in Pharmacology from the University of Gothenburg, Sweden, and her research interests include renorenal reflexes in normotension and hypertension.
Ulla C. Kopp
Datos del fichero:
- Visitas al PDF: 1491
- Descargas totales: 729
- Tamaño del archivo: 640KB
Ver más Libros de Ciencia
Términos de búsqueda:
Neural Control of Renal Function, Second Edition epub, Neural Control of Renal Function, Second Edition gratis completo, Neural Control of Renal Function, Second Edition sin registrarse en pdf
>>> Pero AQUÍ lo tienes GRATIS <<<